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KMID : 0942820110100010029
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Journal of Korean Brain Tumor Society
2011 Volume.10 No. 1 p.29 ~ p.31
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Multicentric Glioblastoma Mimicking Metastatic Brain Tumor
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Lee Su-Whan
Kim Hae-Yu
Lee Sun-Il
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Abstract
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Introduction Multicentric glioblastoma is rare disease entity, which is frequently mimicking metastatic brain tumor. We experienced a case of multicentric glioblastoma which was diagnosed finally after multiple craniotomies for the multicentric intracranial lesions having been believed as metastatic brain tumor. We reported this rare case with literature reviews.
Case Report: A 48-year-old man had underwent Novalis radiosurgery for multiple malignant tumors in other institute. He had no other malignant lesion in other part of body. He was followed up for 10 months and was taken brain magnetic resonance image (MRI) which showed progressed and newly developed intracranial lesions. He visited our institute with the images for Gamma Knife radiosurgery. During follow up after second radiosurgery, he developed neurological symptoms due to increasing intracranial lesions. We performed multiple craniotomies for large two lesions. He gradually recovered after surgery. Pathological report was glioblastoma. He underwent chemotherapy without radiotherapy due to previous radiosurgeries.
Conclusion: This case’s intracranial lesions were considered as metastatic brain tumor undiagnosed primary tumor due to the multicentricity and formation of new lesions for several months. However this was not based on pathological diagnosis which should be necessary to decide precise treatment. This rare case might give us an education about the importance of consideration of invasive procedures for pathological diagnosis in the case of multiple intracranial lesions without evidence of extracranial lesions.
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KEYWORD
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Multicentric glioblastoma, Metastasis, Pathological diagnosis
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